Figure 1.
Late depolarization is independent of NMDAR activity. A, Vm responses of a cell to a flash stimulus before (left) and after (right) MK801 application (10 mg/kg, i.p.) in individual trials (top) and the mean ± SD of all trials (bottom, n = 49 and 30 trials, respectively). E and L represent early and late response periods, respectively. B, Mean depolarization amplitudes of the late responses in the cell shown in A. There were no significant differences between these two conditions (P = 0.30, t77 = 1.06, Student’s t test).