Table 3.

Main findings regarding NY-ESO-1 in cutaneous melanoma

Number / type of melanoma	Frequency of NY-ESO-1	Diagnostic method	Associations found (p<0.05)	Authors
52/20 primary,	33%	PCR		Goydos et al., 2001
22 locoregional
metastases and
10 distant metastases
251 primary and	46% in general	IHC	> Breslow	Barrow et al., 2006
335 metastatic
348 primary	37%	IHC	> Breslow	Svobodova et al., 2011
			< RFS
61 primary	13%	IHC	> Breslow	Velasquez et al., 2007
63 metastatic	32%
89 primary	19%	IHC	> Breslow
			< sup. ext.
			< CD3+	Giavina-Bianchi et al., 2015

IHC = Immunohistochemistry; RFS = relapse free survival; sup. ext. = Superficial extensive histological type