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Induction of adiponectin on human cardiomyocytes (HCM) by endothelin-1 (ET-1). (A) ET-1 stimulation led to an increase, reaching a peak at 48 hrs, in adiponectin protein expression, compared to those incubated with control medium. (B) ET-1 at 100 nM (48 hrs) showed the maximal effect in enhancing adiponectin protein expression in HCM.
* denoted P < 0.05 vs. control. Results are representative of three independent experiments.
