Table 2.

Baseline SARA, UHDRS-IV, PHQ-9, and EQ-5D scores in gait and non-gait-onset groups.

	Regression coefficients of baseline SARA scorea
	SCA1	SCA2	SCA3	SCA6
Age of first visit (yrs)	0.24	0.31***	0.54****	0.35****
Sexb	2.08	−1.25	−0.10	0.29
CAG repeat	0.44	1.00***	1.30****	1.95*
Initial symptomc	−4.89	−2.84	1.97	−2.14

	Regression coefficients of baseline UHDRS-IV scorea
	SCA1	SCA2	SCA3	SCA6
Age of first visit (yrs)	−0.18	−0.14	−0.39****	−0.32****
Sexb	−1.76	0.63	−0.12	0.74
CAG repeat	−0.33	−0.47	−1.16****	−1.64*
Initial symptomc	3.34	1.09	−0.80	2.01

	Regression coefficients of baseline PHQ-9 scorea
	SCA1	SCA2	SCA3	SCA6
Age of first visit (yrs)	0.07	0.01	0.17**	−0.12
Sexb	−0.35	−0.54	1.19	−1.17
CAG repeat	0.22	0.01	0.25	−1.36
Initial symptomc	−7.18	1.00	2.01	1.56

	Regression coefficients of baseline EQ-5D scorea
	SCA1	SCA2	SCA3	SCA6
Age of first visit (yrs)	0.04	0.04	0.09****	0.00
Sexb	−0.05	−0.15	0.05	−0.27
CAG repeat	0.12	0.10	0.22***	−0.20
Initial symptomc	−1.69	0.60	−0.08	0.22

^aAll regression coefficients were calculated in linear regression model, adjusting for age of first visit, sex, CAG repeat and initial symptom.

^bMan = 0, Woman = 1

^cNon-gait-onset = 0, Gait-onset = 1

^*p <0.05

^**p <0.01

^***p <0.005

^****p <0.001

Abbreviations: SARA = Scale for Assessment and Rating of Ataxia; UHDRS = Unified Huntington's Disease Rating Scale; PHQ-9 = Patient Health Questionnaire; EQ-5D = quality of life measurement from 5 domains; SCA = Spinocerebellar Ataxia.