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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: J Neurochem. 2017 May 3;141(5):708–720. doi: 10.1111/jnc.14025

Figure 10.

Figure 10

Elevation of acrolein-lysine level in spinal cord tissue post SCI. Rats were treated by 5mg/kg dimercaprol right after surgery and once a day until 48 hrs after SCI. Photographic dot immunoblotting images (top) show representative blots for each experimental condition. Bar graph (bottom) presents the overall acrolein-lysine conjugate levels for different groups, including sham, non-treated and dimercaprol treated groups. There was a 1.79 ± 0.07 fold elevation of acrolein in the non-treated SCI group comparing to sham group (p<0.005, ANOVA). Dimercaprol treatment reduced acrolein level back to 0.93± 0.10 folds of sham (p<0.001, ANOVA). All data were expressed as mean ± SEM. n = 3–5 in all three groups.