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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: J Neurochem. 2017 May 3;141(5):708–720. doi: 10.1111/jnc.14025

Figure 4.

Figure 4

Dimercaprol protected PC-12 cells from acrolein-mediated cell death based on WST-1 assay. PC-12 cells were exposed to 100 μM acrolein for 4 hrs. Some of them were treated with additional different concentrations of dimercaprol after 15 min of acrolein exposure. Cell viability was tested by WST-1 assay. The cell viability of control (no acrolein or dimercaprol) was considered 100%. The cell viability of other groups was expressed as the percentages of the control. Dimercaprol was capable of significantly protecting PC-12 cells from acrolein-mediated cell death in a dosage-dependent manner starting at a concentration of 50 μM (p<0.05 for 50 μM and p<0.01 for 100 μM when compared to acrolein only, ANOVA). All data were expressed as mean ± SEM, n=7.