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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: J Neurochem. 2017 May 3;141(5):708–720. doi: 10.1111/jnc.14025

Figure 7.

Figure 7

Extended effects of anti-acrolein treatment with dimercaprol based on LDH assay. PC-12 cells were exposed to 100 μM acrolein for 24 hrs. Some of them were treated with either 50 μM or 100 μM dimercaprol after 15 min of acrolein exposure. The anti-acrolein effects of dimercaprol were examined by LDH releasing assay. The release of LDH in control group (no acrolein or dimercaprol) was normalized to 0%. The LDH release for other groups was expressed as the percentages of LDH level when all LDH was released from cells. Dimercaprol significantly reduced acrolein-mediated cell membrane damage (p <0.001 for both dimercaprol concentrations, ANOVA). All data were expressed as mean ± SEM, n=8.