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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: J Neurochem. 2017 May 3;141(5):708–720. doi: 10.1111/jnc.14025

Figure 8.

Figure 8

Extended assessment of cytotoxicity of dimercaprol examined by LDH assay. PC-12 cells were exposed to 50 μM and 100 μM dimercaprol for 4 or 24 hrs. Cell viability was determined by LDH releasing assay. The LDH release in control group (without dimercaprol treatment) was normalized to 0%. The LDH release in other groups was expressed as the percentages of LDH level when all LDH was released from cells. Dimercaprol caused significant cell death when its concentration was at 100 μM when exposure time was 24 hours (* p<0.05, ANOVA). All data were expressed as mean ± SEM, n=5 in 4-hour study and n=8 in 24-hour study.