Figure 1.
Intrathecal delivery A. at the day of surgery, POD0, of RvD1 (■) or RvD2 (●), both at 30ng/30µL), slows the development and prevents the chronic stage of post-thoracotomy-induced mechano-hypersensitivity, shown for the Control group after i.t. injection of vehicle (□, 30µL PBS). B. No difference in the threshold changes from RvD1 delivery occurred when the same i.t. dose was injected on POD4 (●) or POD0 (▲). * p<0.05 for comparison with vehicle-injected rats. † p<0.05 for comparison with baseline, preoperative threshold.