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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: J Pain. 2017 Jan 4;18(5):535–545. doi: 10.1016/j.jpain.2016.12.012

Figure 4.

Figure 4

The Qualitative Hyperalgesia Profile for 5 weeks after thoracotomy A. with vehicle injection on POD0 shows a shift from the baseline (BL) pattern, where either no response (empty bar) or Grade I (diagonal stripes) was observed, to a pattern where all of the rats respond, many with the vigorous nocifensive behaviors of Grade II (cross-hatched) or Grade III (shaded). In contrast, when thoracotomy is preceded by RvD1 (30ng/30µL, i.t.) the majority of rats show the much milder Grade I behavior (see Methods for description). Jonkheere-Terpstra statistics comparing the distributions on the same post-operative day between Thoracotomy with vehicle and that with RvD1 give p values (two-sided) of: Baseline:1.000; POD5:0.687; POD14:0.204; POD36:0.010.