Table 2.

Clusters of activation by simultaneous sensorimotor and emotional stimulation.

Contrast	Region	MNI coordinates (x, y, z)			k	Z values	p values
Analysis of non-flipped data
Patients > controls: (sad-affected > calm-affected) > (sad-unaffected > calm-unaffected)
	Left amygdala	− 16	− 2	− 12	1	3.41	0.038a
	Right amygdala	30	− 4	− 20	1	3.19	0.039b
Analysis of flipped data
Patients > controls: (sad-affected > calm-affected) > (sad-unaffected > calm-unaffected)
	Left amygdala	− 16	− 2	− 12	10	3.35	0.049a
Patients > controls: (sad-affected > calm-affected)
	Left amygdala	− 30	− 4	− 22	11	3. 75	0.013a
Patients > controls: (sad-unaffected > calm-unaffected)
	Right angular gyrus	54	− 60	34	5	5.29	0.006
Functional connectivity - PPI for activation in the left amygdala
Patients > controls: (sad-affected > calm-affected)
	(pre-)Supplemental motor area	8	− 4	66	58	4.24	0.028a
	Right subthalamic nucleus	6	− 20	− 10	5	2.97	0.031b

Local maxima of brain activation in Montreal Neurological Institute (MNI) x-, y-, and z-coordinates with associated Z-score (pFWE < 0.05) and cluster extent in number of voxel (k). R right, L left; abbreviations: PPI = psychophysical interaction, FWE = family-wise error.

^aSmall volume corrected.

^bPost-hoc analysis, small volume corrected.