Table 3.
Changes in Network topology. Repeated-measures ANOVAs were performed examining the effect of level of control (high control vs. low control trial types), effect of group (HC vs. SZ), and group by control interaction in the RiSE and DPX tasks. Analyses examined network topology of the FPN thresholded at a 10% whole-brain level. I = Item stimuli trials in the RiSE task, R = Relational stimuli trials in the RiSE task, A = A Cue trials in the DPX task, B = B Cue trials in the DPX task, HC = Healthy Controls, SZ = individuals with schizophrenia. * indicates FDR corrected within metric at p < 0.05.
| Level of Control: High vs. Low | Group Effect: HC vs. SZ | Group x Control Interaction | ||||
|---|---|---|---|---|---|---|
| RISE E | q-value | F(1,106) | q-value | F(1,106) | q-value | F(1,106) |
| Assortativity | 0.29 | 1.341 | 0.021* (SZ > HC) | 7.443 | 0.29 | 1.13 |
| Global Efficiency | 0.258 | 1.958 | 0.258 | 0.679 | 0.699 | 0.15 |
| Transitivity | 0.661 | 0.379 | 0.661 | 0.514 | 0.661 | 0.193 |
| RISE IR | F(1,106) | F(1,106) | F(1,106) | |||
| Assortativity | 0.072 | 4.408 | 0.072 | 4.015 | 0.264 | 1.26 |
| Global Efficiency | 0.12 | 4.312 | 0.357 | 0.854 | 0.357 | 1.132 |
| Transitivity | 0.027* (I > R) | 7.004 | 0.843 | 0.039 | 0.105 | 3.36 |
| DPX | F(1,95) | F(1,95) | F(1,95) | |||
| Assortativity | 0.814 | 0.056 | 0.003* (SZ > HC) | 10.961 | 0.641 | 0.635 |
| Global Efficiency | 0.183 | 1.8 | 0.039* (HC > SZ) | 6.469 | 0.093 | 3.577 |
| Transitivity | 0.00* (B > A) | 19.378 | 0.005* (HC > SZ) | 9.042 | 0.137 | 2.247 |