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. 2016 Jun 29;11(2):234–239. doi: 10.1007/s12105-016-0740-7

Table 2.

Summary of previously reported cases of CTAT

References Age/gender Anatomic location IHC Metastasis status Treatment Outcome
Bell et al. [3] 58 M Base of tongue (+): CK20, CDX2, beta-catenin, CK7 (focal), MLH1, MSH2, MSH6, PMS2 Positive—1 lymph node Surgery No evidence of recurrence (13 months)
58 M Base of tongue (+): CK20, CDX2, beta-catenin, MLH1, MSH2, MSH6, PMS2 Positive—bilateral lung nodules, multiple lymph nodes Chemotherapy + surgery No evidence of recurrence (11 months)
(−): CK7
Slova et al. [4] 49 M Base of tongue (+): AE1/3, CK20, CK7, CAM5.2, CDX2, villin, EMA, p16, CEA Positive—4/64 lymph nodes Surgery + adjuvant radiation
McDaniel et al. [5] 60 M Anterior tongue (+): CDX2, CK7, CK20 Positive—bilateral cervical lymph nodes Surgery + adjuvant chemotherapy and radiation Recurrence of disease as lung metastases (14 months postoperative); DOD 5 years postoperation
(−): TTF-1
Smith et al. (present case) 53 F Anterior (Oral) tongue (+): AE1/3, CK20, CDX2, SATB2, beta-catenin, MLH1, MSH2, MSH6, PMS2 Negative Surgery + adjuvant radiation No evidence of recurrence or metastasis (8 months)
(−): CK7