Figure 6.

FBA‐based compounds restore TJP‐barrier function improving intestinal permeability. Immunofluorescence staining for occludin (A) and ZO‐1 (C) in colons of DSS‐fed mice treated or not with FBA or butyrate before or after DSS consumption is shown. Scale bar: 100 μm. White arrows indicate areas shown in the inset squares (objective 40×). Quantification of occludin (B) and ZO‐1 (D) expression is reported as integrated pixel intensity (in arbitrary units) per area. Data are presented as means ± SEM, n = 4. * Significant versus CON; # versus DSS.