| TARGETS | |
|---|---|
| Other ion channels a | Enzymes d |
| Ca2+‐activated chloride channels | COX‐2 |
| CFTR | Histone deacetylases (HDACs) |
| GPCRs b | Inducible nitric oxide synthase (iNOS) |
| 5‐HT4 receptor | Microsomal prostaglandin E synthase (mPGES) |
| Adenosine A2A receptor | Myeloperoxidase (MPO) |
| Free fatty acid (FFA) receptors | Cathepsin G |
| M3 receptor | Catalytic receptors e |
| Opioid receptors | Toll‐like receptor (TLR) family |
| Voltage‐gated ion channels c | Nuclear hormone receptors f |
| Transient receptor potential (TRP) channels | Peroxisome proliferator‐activated receptor‐γ |
| LIGANDS | ||
|---|---|---|
| Acetate | IL‐2 | Propionate |
| Acetylcholine | IL‐4 | Serotonin |
| Apigenin | IL‐8 | TNF‐α |
| Bradykinin | IL‐10 | |
| Butyrate | IL‐12 | |
| β‐Catenin | IL‐18 | |
| Curcumin | LTB4 | |
| Histamine | Menthol | |
| IFN‐γ | Mesalamine | |
| IL‐1β | PGE2 |
These Tables list key protein targets and ligands in this article that are hyperlinked to corresponding entries in http://www.guidetopharmacology.org, the common portal for data from the IUPHAR/BPS Guide to PHARMACOLOGY (Southan et al., 2016), and are permanently archived in the Concise Guide to PHARMACOLOGY 2015/16 (a,b,c,d,e,fAlexander et al., 2015a,b,c,d,e,f).