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Higher magnification of Hofbauer cell hyperplasia in the terminal chorionic villi of a placenta from a 21 week gestation infant with intrauterine Zika virus transplacental infection and microcephaly. CD163 antibody. All the brown-staining structures (arrows) are nuclei of Hofbauer cells, which are tightly packed in the villous stroma. The trophoblastic outer layer (arrowheads) of the villi stains blue
