Table 1.

Therapeutic indications for tranexamic acid [27]

Intravenous administration

Prophylaxis and treatment of bleeding due to a local or systemic hyperfibrinolysis in adults and children over the age of 1 year

Bleeding in which hyperfibrinolysis is considered to be involved: Menorrhagia and metrorrhagia Gastrointestinal bleeding Bleeding in urinary tract infections, postoperative bleeding following prostate or urinary tract surgery

Ears, nose and throat (ENT) surgery (adenoidectomy, tonsillectomy, dental extractions)

Gynecological surgery or obstetric hemorrhage

Abdominal and thoracic surgery and other major surgery, e. g. cardiac surgery

As antidote in bleeding requiring immediate treatment while on fibrinolytic treatment

Oral administration

Hypermenorrhea (menorrhagia)

Prostatectomy

Epistaxis

Conisation of the cervix

Prophylaxis of recurrent bleeding in traumatic hyphema

Dental extraction and other interventions in ENT area in patients with hereditary coagulopathies

Mucosal bleeding in patients with coagulopathies

Hereditary angioneurotic edema