Table 7.

Dosing of tranexamic acid in children according to current guidelines (modified according to [108, 109])

Children and adolescents		Bolus	Maintenance dose from day 0
<50 kg	Oral	15–25 mg/kg on preceding evening or 1.5–2× dosage on day of surgery	15–25 mg/kg 3–4× daily
	Intravenous	10–15 mg/kg on day of surgery	10–15 mg/kg 3× daily
≥50 kg	Oral	1.0–1.5 g on preceding evening or 1.5–2× dosage on day of surgery	1.0–1.5 g 3–4× daily
	Intravenous	0.5–1.0 g on day of surgery	0.5–1.0 g 3× daily