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. 2017 May 12;12:73. doi: 10.1186/s13018-017-0572-5

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Changes in disc height index (DHI) after surgery. The operated discs showed a slow, progressive decrease in disc height over time. The DHI in the 16G puncture and annulus defect groups were significantly lower than in the control group (*P < 0.01 vs. control group). The DHI of the PLGA/fibrin gel implantation group was significantly higher than that of the 16G puncture group and annulus defect group over 6 months (^# P < 0.05 vs. 16G puncture group or annulus defect group)