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. 2017 May 12;21:105. doi: 10.1186/s13054-017-1691-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Time course of blood lactate (Lac) levels in cohort 1 animals. a Changes in blood Lac levels during the first 6 h of resuscitation accordingly to study group. b and c Individual arterial Lac levels before starting resuscitation maneuvers (BR) and after the first 6-h resuscitation period (RP 6 h) in the Lac ≥10% and Lac <10% groups. Filled circles in (a) represent animals that died during the 48-h resuscitation period. Red horizontal bars represent median values