Table 2.

Association of demographic and clinical variables with the level of cognition

Model 1
Exposure variable	B Coefficient	95% Confidence interval	p-value
Age (/10 years)	−0.659	−1.04 to −0.28	<0.001
Female	1.321	0.41 to 2.23	0.01
African Americana	−1.189	−2.31 to −0.05	0.04
Other racea	−0.122	−1.71 to 1.47	0.88
College education or above	0.826	−0.04 to 1.70	0.06
H/o diabetes	1.594	0.35 to 2.83	0.01
H/o CAD	−0.158	−1.33 to 1.01	0.79
H/o smoking	−0.573	−1.44 to 0.30	0.20
H/o TIA/stroke	0.381	−2.07 to 2.83	0.76
H/o A.fib	0.787	−0.65 to 2.22	0.28
BMI (≥30 kg/m2)	0.343	−0.52 to 1.20	0.43
Serum hemoglobin (per g/dl)	−0.137	−0.38 to 0.11	0.27
eGFR (per ml/min/1.73 m2)	−0.005	−0.03 to 0.02	0.62
SBP (per mm Hg)	−0.011	−0.04 to 0.02	0.44
DBP (per mm Hg)	0.042	0.001 to 0.08	0.05
Time on dialysis (per year)	−0.104	−0.31 to 0.11	0.33
Time since KT (per year)	0.005	−0.11 to 0.12	0.93
ESRD secondary to diabetesb	0.027	−1.33 to 1.38	0.97
Model 2
Exposure Variable	B Coefficient	95% Confidence interval	p-value
Age (/10 years)	−0.669	−1.00 to −0.34	<0.001
Female	1.363	0.50 to 2.23	0.002
College education or above	0.922	0.09 to 1.76	0.03
H/o diabetes	1.455	0.56 to 2.35	0.002
H/o smoking	−0.491	−1.34 to 0.36	0.25
H/o A. fib	−0.759	−0.58 to 2.10	0.27
Serum hemoglobin (per g/dl)	−0.120	−0.33 to 0.09	0.27
DBP (per mm Hg)	0.026	−0.01 to 0.06	0.15
Time on dialysis (per year)	−0.000	−0.35 to 0.04	0.12

Model 1 includes all variables of interest entered in the multivariable analysis. All variables are adjusted for the other variables. Models 2 includes variables selected on the basis of their predictive relevance using adjusted R-square criterion

H/o history of, ESRD end stage renal disease, TIA transient ischemic attack, BMI body mass index, eGFR estimated glomerular filtration rate, SBP systolic blood pressure, DBP diastolic blood pressure, KT kidney transplant

^areference group: Caucasian race. ^breference group: other causes of ESRD