Table 4.

Transfusion and chest tube output data in HFC group (n=22) and contemporary propensity matched controls (n=22) undergoing elective proximal thoracic aortic surgery including hemi-arch replacement with DHCA and not receiving study drug.

Outcome	HFC (n=22)	No HFC (n=22)	p-value
Total Cell Saver (mL)	643 (474–879)	500 (288–750)	0.20
Intraoperative PRBC
Number of Patients Transfused (%)	10 (45.5%)	11 (50.0%)	0.99
Median (IQR) Units Among Patients Transfused	1.5 (1, 2)	3 (2, 3)	0.02
Intraoperative FFP
Number of Patients Transfused (%)	19 (86.4%)	21 (95.5%)	0.61
Median (IQR) Units Among Patients Transfused	4 (4, 6)	5 (4, 8)	0.15
Intraoperative Platelets
Number of Patients Transfused (%)	20 (90.9%)	22 (100%)	0.49
Median (IQR) Units Among Patients Transfused	2 (2, 3)	2 (2, 3)	0.73
Intraoperative Cryoprecipiate
Number of Patients Transfused (%)	3 (13.6%)	12 (54.5%)	0.01
Median (IQR) Units Among Patients Transfused	1 (1, 1.5)	1 (1, 1)	0.33
Postoperative PRBC
Number of Patients Transfused (%)	6 (27.3%)	1 (4.5%)	0.09
Median (IQR) Units Among Patients Transfused	1 (1, 1.8)	1	0.53
Postoperative FFP
Number of Patients Transfused (%)	1 (4.5%)	0	0.99
Postoperative Platelets
Number of Patients Transfused (%)	1 (4.5%)	0	0.99
Postoperative Cryoprecipitate
Number of Patients Transfused (%)	0	0	NA
24hr Postoperative Chest Tube Drainage (mL)	525 (388–720)	570 (493–795)	0.16
Intraoperative Factor VIIa Administration	2 (9.1)	4 (18.2)	0.37
Postoperative Factor VIIa Administration	0	0	NA

DHCA=deep hypothermic circulatory arrest; SD=standard deviation; PRBCs=packed red blood cells; FFP=fresh frozen plasma; POD=post-operative day; NA=not applicable