Table 2.
Association between GlycA, coronary artery disease and mortality, stratified by diabetes status.a
| CAD
|
All-cause mortality
|
|||
|---|---|---|---|---|
| Basic OR (CI) | Adjusted OR (CI)b | Basic HR (CI) | Multivariable HR (CI) a | |
| Full population | 1.14 (1.09–1.20), P <0.0001 | 1.07 (1.02–1.13), P = 0.013 | 1.39 (1.34–1.44), P <0.0001 | 1.34 (1.29–1.39), P <0.0001 |
|
| ||||
| Diabetes | 1.01 (0.92–1.11), P = 0.078 | 1.03 (0.93–1.14), P = 0.58 | 1.30 (1.24–1.37), P <0.0001 | 1.28 (1.21–1.36), P <0.0001 |
|
| ||||
| No diabetes | 1.14 (1.07–1.21), P <0.0001 | 1.09 (1.02–1.16), P = 0.009 | 1.42 (1.36–1.48), P <0.0001 | 1.38 (1.32–1.45), P <0.0001 |
|
| ||||
| Cardiovascular mortalityc | ||||
|
| ||||
| 1.37 (1.30–1.45) P <0.0001 | ||||
|
| ||||
| Noncardiovascular mortality | ||||
|
| ||||
| 1.47 (1.39–1.54) P <0.0001 | ||||
|
| ||||
| Other mortality | ||||
|
| ||||
| 1.23 (1.10–1.38) P <0.001 | ||||
a
HR per 1 SD increase in GlycA concentrations.
b
Adjusted for age, sex, race, BMI, diabetes, hypertension, smoking, hyperlipidemia, and LDL-P, and additionally for presence of CAD and ejection fraction in mortality models.
c
Multivariable model HR for CV mortality in the full population.