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. 2017 Apr 10;7:780. doi: 10.1038/s41598-017-00700-z

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Biomechanical properties of tendon repair tissues 2 weeks after Achilles tenotomy. Biomechanical tests comparing maximum tensile load of the repair tissues 2 weeks after surgery revealed no significant difference (p > 0.05; Mann-Whitney test, two-tailed) between the experimental groups (a). Tendon stiffness measurements 2 weeks after surgery among the experimental groups showed significantly stiffer repair tissues (p < 0.05, asterisk; Mann-Whitney test, two-tailed) in the high-glucose group (n = 14) when compared to the control group (n = 14) (b). Values for intact tendons are provided as a reference (n = 9). Representative force-elongation diagrams of the repair tissues of the control diet group (c), the high-glucose diet group (d) and of an intact tendon (e). In the toe-region collagen fibres are crimped and become elongated and straightened with applied loading. The linear region represents tendon stiffness. Microscopic tears occur in the plastic region where the slope drops until the maximum tensile load is reached and the tendon ruptures.