Figure 4.
Effect of L-NAME or ODQ on SF-induced relaxation. (A) Endothelium-intact rings were incubated with cumulative doses of SF in the absence (circles) or presence of L-NAME (100 µM; squares. Data represent mean ± SEM (n = 7; p < 0.01 for Salvia versus L-Name plus Salvia). (B) Endothelium-intact rings were incubated with cumulative doses of SF in the absence (circles) or presence of ODQ (1 µM; squares). n = 7; p < 0.01 for Salvia versus ODQ plus Salvia. (C) Endothelium-intact rings were incubated with increasing doses of SF and levels of NO determined. n = 3; *denotes a p < 0.05 and **a p < 0.01 (compared to control).