Table 1.

Characterization of SOF/TIBA/PLGA MSs.

Composition	Mean diameter (μm)	SOF encapsulation efficiency (%)	SOF content (%)
SOF/TIBA/PLGA05 MSs (SOF:PLGA = 0.5:20)	25.1 ± 0.4	42.00 ± 1.01	1.02 ± 0.02
SOF/TIBA/PLGA10 MSs (SOF:PLGA = 1:20)	24.8 ± 0.3	48.70 ± 1.42	2.32 ± 0.07
SOF/TIBA/PLGA20 MSs (SOF:PLGA = 2:20)	28.5 ± 2.1	58.20 ± 0.79	5.11 ± 0.07

The ratio between SOF and PLGA is presented as the input amounts of materials.

Data are presented as mean ± standard deviation (SD) (n = 3).

$\mathrm{{\rm E}}\mathrm{ncapsulation}\mathrm{efficiency}(\%)=\frac{\mathrm{actual}\mathrm{amount}\mathrm{of}\mathrm{SOF}\mathrm{in}\mathrm{MSs}}{\mathrm{input}\mathrm{amount}\mathrm{of}\mathrm{SOF}\mathrm{in}\mathrm{MSs}}\times \mathrm{100}$.

$\mathrm{Drug}\mathrm{content}(\%)=\frac{\mathrm{actual}\mathrm{amount}\mathrm{of}\mathrm{SOF}\mathrm{in}\mathrm{MSs}}{\mathrm{amount}\mathrm{of}\mathrm{SOF}-\mathrm{loaded}\mathrm{MSs}}\times \mathrm{100}$.