Table 2.
Statistical calculations for high IGF-1/low miR-181 status.
| Covariate | Hazard Ratio | 95% Conf-U | 95% Conf-L | stdErr | p. value |
|---|---|---|---|---|---|
| High IGF1/Low miR-181d | 1.435 | 1.956 | 1.053 | 0.158 | 0.022 |
| G-CIMP | 3.876 | 7.547 | 1.991 | 0.34 | <0.001 |
| Age > 60 | 1.433 | 1.942 | 1.058 | 0.155 | 0.02 |
| Karnofsky score ≥ 80 | 1.988 | 2.807 | 1.408 | 0.176 | <0.001 |
| Gender (male) | 1.061 | 1.446 | 0.778 | 0.158 | 0.708 |
IGF1-miR-181 status is a strong and independently significant prognostic factor among Karnofsky performance status, age, gender and CIMP status. stdErr: stander error; Conf-L/U: Confidence interval lower limit/upper limit.