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. 2017 Apr 7;7:754. doi: 10.1038/s41598-017-00856-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Network and expression levels of 51 top hub genes in brown module. (a) Cytoscape network visualization of 51 genes, in which only edges with weight (w) above a threshold of 0.2 are displayed. The red nodes denote lncRNA genes. The green and blue nodes both denote protein-coding genes, but the green color stands for genes with function in maintaining genomic stability. (b) The expression levels of 51 genes in each cancer type. The y axis represents the average FPKM value of samples in each group. And the blue and red colors denote protein-coding genes and onco-lncRNAs, respectively.