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. 2017 Apr 6;7:717. doi: 10.1038/s41598-017-00851-z

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of NMN on brain cell death and oxidative stress in mouse cICH model. (A) Representative images and quantitative analysis of TUNEL staining at 24 hours post cICH. **P < 0.01, n = 5 per group. (B) Oxidative parameters in hemorrhagic brain tissue, including MDA, H₂O₂, O²⁻, CuZn/Mn-SOD, total-antioxidant activity, were determined at 24 hours post cICH. *P < 0.05, n = 6 per group. (C) Representative images and quantitative analysis of NOX-1 immunohistochemistry staining at 24 hours post cICH. **P < 0.01, n = 5 per group.