Table 2.
Animal characteristics and liver composition of wild-type and PPARδIEC-KO mice after a LFD (n = 3–8) or HFD (n = 4–10).
| wild-type LFD | PPARδIEC-KO LFD | wild-type HFD | PPARδIEC-KO HFD | |
|---|---|---|---|---|
| Food intake (g/24 h) | 2.8 ± 0.6 | 2.3 ± 0.6 | 2.7 ± 0.5 | 2.9 ± 0.5 |
| Body weight (g) | 30.0 ± 2.1 | 29.2 ± 3.1 | 39.1 ± 4.3 | 44.4 ± 6.2 |
| Liver weight (% of body weight) | 3.6 ± 0.3 | 2.9 ± 0.5 | 2.6 ± 0.6* | 3.1 ± 0.7 |
| Liver cholesterol (µmol/g) | 6.0 ± 2.3 | 5.2 ± 0.6 | 6.4 ± 1.3 | 5.1 ± 2.0 |
| Liver TG (µmol/g) | 2.5 ± 2.1 | 2.6 ± 1.0 | 6.7 ± 10.1 | 6.5 ± 10.5 |
| Liver phospholipids (µmol/g) | 26.6 ± 1.6 | 25.0 ± 0.6 | 27.9 ± 2.1 | 26.7 ± 2.8 |
| Plasma TG (mmol/l) | 0.7 ± 0.4 | 0.6 ± 0.2 | 0.5 ± 0.2 | 0.5 ± 0.2 |
| Plasma cholesterol (mmol/l) | 3.3 ± 0.3 | 2.6 ± 0.9 | 4.2 ± 0.6 | 5.0 ± 0.7### |
*Significantly different from wild-type on LFD (p < 0.05); ###Significantly different from PPARδIEC-KO on LFD (p < 0.001). Values are presented as means ± SD.