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. 2017 Apr 12;7:843. doi: 10.1038/s41598-017-00927-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Thrombin generation in plasma diluted with PEs. (a) – The curves of thrombin generation in plasma diluted with NS (one of the typical experiments). The values of DF were equal to: (1) – 1.025 (plasma, practically undiluted); (2) – 1.5; (3) – 2; (4) – 3; (5) – 4. (b) – The typical dependencies of ETP (in %) versus DF obtained in one of the experiments for plasma diluted with different PEs (see legend to Fig. 1): (1) – NS; (2) – RPG; (3) –HES; (4) – GF; (5) – ALB. DF (a dilution factor) is equal to the ratio of the final volume of diluted plasma to its initial volume.