Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Apr 18;7:897. doi: 10.1038/s41598-017-00952-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Bar graphs summarizing the pathway and GO enrichment analysis for the different substructures of hippocampus. (a) Top 10 significant GO terms associated with the genes expressed in each of the hippocampal substructures. The horizontal axis represents the –log10 (p-value) for the GO terms represented on the vertical axis. Enrichment of terms related to neurogenesis and neuronal differentiation was found specific to dentate gyrus (DG) and cornus ammonis (CA4) regions, while synapse-associated genes are particularly enriched in CA4 region. (b) KEGG pathway enrichment had neurotrophin signaling, neuroactive ligand-receptor interaction and long term potentiation as the top enriched brain tissue-specific pathways. This pathway image is obtained from KEGG^{77, 78}. (c) Long-term potentiation pathway mapped with the genes enriched in DG is known for its role in neurogenesis and other hippocampus specific functions. The genes of interest have been highlighted in red color.