Table 1.
Region | Side | Coordinates | Cluster Size (mm3) | Z values (peak) | Corrected p |
---|---|---|---|---|---|
CAPS Effects (negative)
| |||||
Superior frontal | L | −7, 49, 34 | 6847 | − 6.5 | < 0.001 |
Isthmus of cingulate | L | 1410 | − 5.9 | ||
−9, −48, 28 | < 0.001 | ||||
Insula | L | 1315 | − 3.5 | ||
−30, 12, 6 | < 0.001 | ||||
Superior frontal | R | 13, 46, 34 | 1183 | − 3.6 | |
< 0.001 | |||||
Postcentral | L | 867 | − 4.4 | ||
−14, −31, 71 | < 0.001 | ||||
Caudal middle frontal | L | 857 | − 4.0 | ||
−25, −3, 41 | < 0.001 | ||||
Superior Parietal | L | 652 | − 3.8 | ||
−32, −47, 33 | 0.001 | ||||
Lateral orbitofrontal | R | 42, 25, −12 | 626 | − 3.5 | |
0.002 | |||||
Posterior cingulate | R | 5, 7, 35 | 603 | − 4.2 | |
0.002 | |||||
Lateral occipital | R | 25, −83, 19 | 602 | − 4.0 | |
0.003 | |||||
Lateral occipital | R | 20, −84, −1 | 511 | − 2.8 | |
0.009 | |||||
CES Effects (negative) | |||||
Rostral middle frontal | L | 30, 36, 19 | 813 | − 3.9 | < 0.001 |
Diagnosis (PTSD vs. CC) * CES Interaction | |||||
Supramarginal | L | −46, −31, 18 | 1200 | 4.0 | < 0.001 |
Cuneus | L | 1147 | 4.9 | ||
−11, −76, 29 | < 0.001 | ||||
Superior frontal | L | 1080 | 4.4 | ||
−8, 28, 51 | < 0.001 | ||||
Cuneus | R | 5, −83, 21 | 865 | 3.6 | |
< 0.001 | |||||
Paracentral | R | 6, −10, 58 | 534 | 3.1 | |
0.007 | |||||
Precentral | L | 523 | 2.8 | ||
−40, −10, 44 | 0.008 | ||||
Paracentral | L | 514 | 3.5 | ||
−7, −27, 55 | 0.009 |
Abbreviations – CC: combat control; PTSD: posttraumatic stress disorder; PFC: prefrontal cortex; L: left; R: right; CAPS-IV: Clinician Administered PTSD Scale for the DSM-IV; CES: Combat Exposure Scale.