. Author manuscript; available in PMC: 2018 Jun 1.

Published in final edited form as: Transl Res. 2017 Feb 21;184:77–100. doi: 10.1016/j.trsl.2017.02.002

Table 1.

Phenotypic markers and key properties of vascular precursor cells

Precursor cell	Origin		Phenotypic markers
EPC	Human		CD45⁻CD34⁺CD133⁺VEGFR-2(KDR)⁺
	Mouse		Lin⁻c-kit⁺Sca1⁺VEGFR-2(Flk1)⁺
	Rat		Lin⁻Hoechst⁺CD36⁺
	Rabbit		CD34⁺VEGFR-2⁺UEA1⁺ with positive for uptake of acetylated low-density lipoprotein
MSC	Human		1) Plastic-adherent when maintained in standard culture conditions;
			2) CD105⁺CD73⁺CD90⁺CD45⁻CD34⁻CD14⁻CD11b⁻CD79α⁻CD19⁻HLA-DR⁻;
			3) Differentiation into osteoblasts, adipocytes, and chondroblasts
Pericyte	Human		CD34⁻CD31⁻CD45⁻CD56⁻CD146⁺PDGFRβ⁺
		Capillary	NG2⁺aSMA⁻
		Venule	NG2⁻aSMA⁺
		Arteriole	NG2⁺aSMA⁺
	Mouse		CD31⁻CD146⁺PDGFRβ⁺NG2⁺
SMPC	Human		(PDGFR-β⁺CPM⁺CA12⁺RAMP1⁺LRP1⁺)?
Vascular wall SPC	Human		CD31⁻CD34⁺VEGFR(KDR)⁺TIE2⁺
			C-kit⁺
	Mouse		Lin⁻c-kit^−/lowSca1⁺CD34^−/low