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. 2017 Apr 30;2017:4951937. doi: 10.1155/2017/4951937

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Copyright © 2017 Maryem Ben Salem et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Histopathological slides tissues of paw oedema in experimental groups of rats. (a) Control group; untreated group. (b) Carr group; Carr-treated rat showed heavy infiltration of polynuclear neutrophils (PN) and a spongy-like appearance and bulla in the epidermis. (c) Carr + EtOH extract group; Carr-treated rat that received the EtOH extract (400 mg/kg/bw) reduced significantly the migration of PN and oedematasis in dermis without any spongy-like feature and bulla. (d) Carr + Indo group; Carr-treated rat that received Indomethacin (10 mg/kg/bw) showed a partial protective action. Deparaffinized hematoxylin and eosin (H&E) stained sections (200–400x). Plus sign: infiltration of PN. Arrow: odematasis in the epidermis.