Table 7.
Effect of Cynara scolymus leaves extract on carrageenan-induced rat paw oedema.
| Treatment | Oedema size (mean ± SD) (mm) | |||||
|---|---|---|---|---|---|---|
| 0 h | 1 h | 2 h | 3 h | 4 h | 5 h | |
| Control | 0.426 ± 0,00 | 0.441 ± 0.01 | 0.56 ± 0.03 | 0.650 ± 0.05 | 0.755 ± 0.05 | 0.70 ± 0.01 |
| Carr | 0.426 ± 0,00 | 2.8 ± 0.26α∗∗∗ | 3.33 ± 0.28α∗∗∗ | 3.25 ± 0.02α∗∗∗ | 3.15 ± 0.01α∗∗∗ | 3.02 ± 0.09α∗∗∗ |
| Carr + Indo (10 mg/kg) | 0.426 ± 0,00 | 2.46 ± 0.26α∗∗∗β∗ | 2.61 ± 0.07α∗∗∗β∗∗∗ | 2.30 ± 0.02α∗∗∗β∗∗∗ | 1.8 ± 0.11α∗∗∗β∗∗∗ | 1.4 ± 0.06α∗∗∗β∗∗∗ |
| Carr + ALE (400 mg/kg/bw) |
0.426 ± 0,00 | 2.480 ± 0.05α∗∗∗β∗∗∗ | 1.88 ± 0.04α∗∗∗β∗∗∗£∗∗∗ | 1.65 ± 0.05α∗∗∗β∗∗∗£∗∗∗ | 1.16 ± 0.20α∗∗∗β∗∗∗£∗∗∗ | 1.12 ± 0.1α∗∗∗β∗∗∗£∗∗∗ |
Values represent means ± SD (n = 6) in each group. ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001.
α: compared to control; β: compared to Carr; £: compared to Carr + Indo.