Table 2.
Comparison of COS and IVF outcomes among the three groups.
| Variables | ANA+/anti-dsDNA+ group (n = 52) |
ANA+/anti-dsDNA− group (n = 86) |
ANA−/anti-dsDNA− group (n = 121) |
P value |
|---|---|---|---|---|
| Stimulation length (d) | 11.06 ± 1.75 | 11.07 ± 1.70 | 10.80 ± 1.98 | 0.663 |
| Total Gn dose (IU) | 2404.17 ± 797.50 | 2400.24 ± 784.28 | 2337.06 ± 846.77 | 0.634 |
| E2 level on HCG day (pg/ml) | 3087.08 ± 927.41 | 3086.66 ± 1000.67 | 3183.55 ± 1086.38 | 0.866 |
| Endometrial thickness on HCG day (mm) |
10.50 ± 1.61 | 10.85 ± 1.80 | 10.67 ± 1.11 | 0.568 |
| Number of retrieved oocytes | 9.81 ± 1.19A,C | 12.52 ± 3.50 | 12.89 ± 3.24 | <0.001 |
| Fertilization rate | 51.0% (260/510) A,B,C | 57.9% (624/1077) | 69.0% (1076/1560) | <0.001 |
| Number of embryo transferred | 2.04 ± 0.19 | 2.01 ± 0.11 | 2.02 ± 0.29 | 0.779 |
| Available embryos | 4.15 ± 0.85A,B,C | 5.24 ± 1.23 | 5.81 ± 0.91 | <0.001 |
| High-quality embryos | 2.13 ± 0.34A,B,C | 2.99 ± 0.83 | 3.36 ± 0.79 | <0.001 |
| Implantation rate | 9.4% (10/106) B,C | 15.0% (26/173) | 25.8% (63/244) | <0.001 |
| Clinical pregnancy rate | 11.5% (6/52) A,B,C | 30.2% (26/86) | 47.1% (57/121) | <0.001 |
| Early miscarriage rate | 100% (6/6) | 38.5% (10/26) | 22.8% (13/57) | — |
A, B, C P < 0.05 was considered to be statistically significant among the three groups. P < 0.0167 was considered to be statistically significant between any two groups. P < 0.0167 versus those of the groups ANA+/anti-dsDNA+ and ANA+/anti-dsDNA−. P < 0.0167 versus those of the groups ANA+/anti-dsDNA− and ANA−/anti-dsDNA−. P < 0.0167 versus those of the groups ANA+/anti-dsDNA+ and ANA−/anti-dsDNA−.