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| Low Arousal Threshold | High Arousal Threshold |
|---|---|
| Higher propensity to wake up from sleep | Lower propensity to wake up from sleep |
| More likely to have mild-to-moderate OSA | Predominantly associated with severe OSA |
| Sedatives may be beneficial | Sedatives may evoke a respiratory arrest |
| Associated with less hypoxia due to reduced apnea duration | More prone to hypoxia due to prolonged apneas |
Abbreviation: OSA, obstructive sleep apnea.
