Table 5.

C-indices and 95% confidence intervals estimated at 1, 3, and 5 years after transplantation under a competing-risk model, treating death with allograft function as a competing outcome

Measure	One year after transplantation		Three years after transplantation		Five years after transplantation
	Current KDRI	Revised KDRI	Current KDRI	Revised KDRI	Current KDRI	Revised KDRI
AUC 1 for allograft failure	0.674(0.591,0.757)	0.674(0.593,0.755)	0.629(0.567,0.692)	0.639(0.578,0.700)	0.646(0.583,0.710)	0.657(0.593,0.721)
AUC 2 for allograft failure	0.671(0.588,0.755)	0.672(0.591,0.753)	0.618(0.556,0.68)	0.629(0.568,0.69)	0.626(0.564,0.688)	0.633(0.57,0.696)
AUC 1 for death with a functioning graft	0.579(0.47,0.688)	0.567(0.462,0.673)	0.627(0.546,0.708)	0.62(0.541,0.699)	0.642(0.566,0.719)	0.670(0.591,0.749)
AUC 2 for death with a functioning allograft	0.568(0.464,0.672)	0.556(0.447,0.664)	0.608(0.53,0.685)	0.598(0.518,0.678)	0.611(0.534,0.687)	0.636(0.562,0.710)

AUC 1 and AUC 2 are defined following Blanche and colleagues (17). AUC 1 refers to the estimated c-index, assuming controls are free of either event (subjects who are alive with a functioning allograft) before the time point of interest. AUC 2 focuses on each specific type of failure; therefore, an AUC 2 estimate for allograft failure (e.g., at 3 years) assumes that controls are alive at 3 years after transplantation.

AUC, area under the curve