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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Osteoarthritis Cartilage. 2016 Nov 14;25(6):914–925. doi: 10.1016/j.joca.2016.11.004

Figure 6. Effect of longer and sustained CCR2 blockade on pain response.

Figure 6

Pain measures (N=4 for each of the experimental points described) were obtained by assessing the weight shift from the operated (right) limb to the un-operated (left) limb, in mice 8 and 12 wks after DMM/sham surgery, with or without RS-504393 treatment at the time indicated in Fig. 5A (1-to-8wks or 1-to-12wks) (Incapacitance meter). The graph represents the mean ± standard deviation. Significance was set at P < 0.05.