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. 2017 May 15;8:294. doi: 10.3389/fphys.2017.00294

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Copyright © 2017 Wan, Bao, Huang, Zhang, Liu, Cui, Jiang, Wang, Liu and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of supaglutide on food intake and energy expenditure in the DIO mice. (A) Food intake. Oxygen consumption (VO2) expressed as per mouse in (B) and normalized by body weight (BW) in (C). Carbon dioxide release (VCO2) expressed as per mouse in (D) and normalized by BW in (E). Energy expenditure (EE) expressed as per mouse in (F) and normalized by BW in (G). Significant difference between control and SPG is determined using unpaired Student's t-test. All values are means ± SE (n = 4 for each group). ^*p < 0.05; ^**p < 0.01.