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. 2017 May 15;10:129. doi: 10.3389/fnmol.2017.00129

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Copyright © 2017 Brownlow, Jung, Moore, Bechmann and Jankord.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Hippocampal levels of β-hydroxybutyrate (BHB) and brain derived neurotrophic factor (BDNF). (A) Daily exposure to stress resulted in decreased hippocampal levels of BHB. This decrease, however, was attenuated in KD-fed rats compared with stressed rats on control diet (indicated by bracket with arrows). (B) Decreased BDNF levels were observed in stressed NIH-31 fed rats compared with non-stressed NIH-31 fed rats. However, both KD and KS groups showed a non-significant trend (p = 0.10) for lower levels of hippocampal BDNF. Data shown as mean ± S.E.M. (n = 8–10/group). ^*p ≤ 0.05; ^**p < 0.01.