Table 3.

Univariate and multivariate analyses of OS in the nonsurgery cohort

Variables	Univariate analysis	Multivariate analysis
	P value	HR (95% CI)	P value
Agea (years)	<0.001
18–44		Reference
45–54		1.130 (0.891–1.433)	0.313
55–64		1.151 (0.914–1.449)	0.232
65–74		1.702 (1.346–2.152)	<0.001
75+		3.381 (2.659–4.299)	<0.001
Race	<0.001
White		0.676 (0.594–0.770)	<0.001
Black		Reference
Otherb		0.920 (0.729–1.161)	0.481
Sex	<0.001
Female		Reference
Male		0.781 (0.702–0.868)	<0.001
Marital status	<0.001
Unmarried		1.493 (1.364–1.635)	<0.001
Married		Reference
Grade	<0.001
I		1.273 (1.094–1.482)	0.002
II		Reference
III		0.772 (0.704–0.847)	<0.001
IV		0.836 (0.565–1.235)	0.367
T stage	<0.001
T1		Reference
T2		1.482 (1.279–1.717)	<0.001
T3		2.190 (1.865–2.572)	<0.001
T4a		2.798 (2.397–3.265)	<0.001
T4b		3.557 (2.793–4.531)
N stage	<0.001
N0		Reference
N1		0.979 (0.859–1.115)	0.750
N2a		0.715 (0.579–0.883)	0.002
N2b		0.902 (0.790–1.030)	0.127
N2c		1.116 (0.980–1.272)	0.098
N3		1.154 (0.943–1.411)	0.165
M stage	<0.001
M0		Reference
M1		2.095 (1.761–2.494)	<0.001
Radiation	<0.001
M0		Reference
M1		0.341 (0.305–0.381)	<0.001
Radiation	<0.001
Yes		0.341 (0.305–0.381)	<0.001
None		Reference

CI; confidence interval; HR, hazard ratio.

^aAge at diagnosis.

^bOther including American Indian/AK Native, Asian/Pacific Islander.