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. 2017 Apr 4;6(5):1062–1071. doi: 10.1002/cam4.1039

Figure 7.

Figure 7

Suppression of AKT signaling pathway reverses CCL19‐induced MCF‐7 cells migration, invasion, and the secretion of MMP‐2/9. (A) SiAKT1 affects pAKT expression by western blot. (B) SiAKT1 affects CCL19‐induced cell migration. (C) Si AKT1 affects CCL19‐induced cell invasion. All data are presented as mean  ±  SD from three independent experiments. *P < 0.05 (as compared with control group), # P < 0.05(as compared with CCL19 group). (D) MCF‐7 cells transfected with SiCCR7 were treated with or without LY294002, and the MMP2/9 activity expression by ELISA. All data are presented as mean  ±  SD from three independent experiments. *P < 0.05 (as compared with control group), # P < 0.05(as compared with the CCR7 silencing or treatment with the inhibitor alone group).