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Comparison of the methylation level of Group 1 markers. All Group 1 markers showed that HME CRCs presented higher methylation levels than LME and IME CRC. Similarly, all the Group 1 markers showed significantly higher methylation levels in BRAF‐mutation(+) CRC than in KRAS‐mutation(+) and NRAS‐mutation(+) CRC (*P < 0.05).
