Skip to main content
. 2017 Apr 4;6(5):1023–1035. doi: 10.1002/cam4.1061

Figure 6.

Figure 6

Comparison using linear single regression model. (A) Association of methylation accumulation with age. CRC samples of elder patients showed significantly higher methylation levels in Group 1 markers, for example., MLH1, than in Group 2 markers, for example., UCHL1 (see Fig. S1). (B) Association of methylation accumulation with location. Group 2 markers, for example., UCHL1, and Group 1 marker, for example., MLH1, showed significant correlation between higher methylation levels and proximal location (Fig. S2). Since 6 Group 1 markers and 13 Group 2 markers were evaluated for each factor, P < 0.008 (i.e., 0.05/6) and P < 0.004 (i.e., 0.05/13) were considered significant in the analysis of Group 1 and Group 2 markers, respectively, instead of P < 0.05 (*).