Figure 5.
(A) Effect of AZD4547 on apoptosis of FGFR2-amplified PDCs. The AZD4547-treated PDC culture showed a higher apoptotic cell population (11.3%) than the control cell culture (0.65%) (P < .001). (B) Flow cytometry analysis of cell cycle of PDCs treated with 1 μM AZD4547 for 5 days. Cell cycle progression was analyzed using propidium iodide.