Figure 3. Ca²⁺‐activated secretory events at the apical pole of pancreatic acinar cells.

Simultaneous recording of changes in Cl⁻ conductance (ΔG) and capacitance (ΔC) during a single IP₃‐elicited Ca²⁺ spike (part of a train of spikes evoked by continuous intracellular IP₃ infusion) shows the similar timing and trend of both events with a slight delay in the capacitance increase as compared to the rise of the Cl⁻ conductance. It is also seen that the Cl⁻ conductance increase outlasts the period of increased capacitance. From Maruyama & Petersen (1994).