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. 2017 Apr 19;7:940. doi: 10.1038/s41598-017-01078-8

Table 3.

Bias factor on the different responses in HEK293 and mLTC-1 cells.

HEK293 cells Bias factor mLTC-1 cells Bias factor
ß-arrestin 2/cAMP 1.81 (p = 0.0655) cAMP/Progesterone 5.25 (p = 0.0034)
Cre -reporter assay/cAMP 4.84 (p = 0.0000177) cAMP/Testosterone 2.39 (p = 0.0301)
Cre -reporter assay/ß-arrestin 2 2.67 (p = 0.00988) Testosterone/Progesterone 2.19 (p = 0.0617)

The bias factor values of each response pair reflect the biased agonism of rhLH towards the first response compared to the second, all in comparison to rhCG taken as the reference hormone.