Table 3.
Incidence of DRPs in the polypharmacy groups
SCI |
Control |
|||
---|---|---|---|---|
High-risk drug class | Number of subjects on class at time of DRP | % of subjects with a DRP | Number of subjects on class at time of DRP | % of subjects with a DRP |
Narcotics | 273 | 43% | 30 | 14% |
Anticonvulsants | 191 | 30% | 25 | 11% |
Serotoninergics | 187 | 29% | 40 | 18% |
Antianxiety | 147 | 23% | 19 | 9% |
Skeletal muscle relaxants | 105 | 16% | 8 | 4% |
Sedatives | 87 | 14% | 14 | 6% |
Tricyclic antidepressants | 31 | 5% | 8 | 4% |
Total | 637 | 217 |
Table 3 demonstrated the percentage of individuals who had a reported DRP and were taking a medication within one of the high-risk classes of drugs (8.6 vs. 2.13; P < 0.05). For example, 43% of individuals with SCI who were on a narcotic also reported a DRP compared to 14% of controls.